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Case Report
Online Published: 03 Jan 2021
 


Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report

Cucunawangsih Cucunawangsih, Andree Kurniawan, Nata Pratama Hardjo Lugito.


Abstract
Micafungin is an echinocandin-class antifungal agent that is extremely used in the recent era due to minimal toxicity and broad-spectrum activity, unfortunately has limited ability against Cryptococcus neoformans. Since it’s inherently resistant, indeed disseminated invasive cryptococcosis is becoming an important issue in echinocandin recipient with impaired immunity. We present a patient with systemic lupus erythematosus and miliary tuberculosis, who developed a fungal infection with invasive cryptococcal fungemia during empirical micafungin therapy. To the best of our knowledge, breakthrough disseminated cryptococcosis has not been reported, as seen in our patient. This case highlighted that Cryptococcus neoformans infection should be kept in mind as a possible breakthrough infection while receiving echinocandin, especially in patients with cellular immunodeficiency.

Key words: invasive fungal infection, micafungin, Cryptococcus neoformans


 
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How to Cite this Article
Pubmed Style

Cucunawangsih C, Kurniawan A, Lugito NPH. Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. Int J Med Rev Case Rep. 2021; 5(2): 25-30. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia

Web Style

Cucunawangsih C, Kurniawan A, Lugito NPH. Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. https://www.mdpub.net/?mno=13481 [Access: April 02, 2025]. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia

AMA (American Medical Association) Style

Cucunawangsih C, Kurniawan A, Lugito NPH. Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. Int J Med Rev Case Rep. 2021; 5(2): 25-30. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Vancouver/ICMJE Style

Cucunawangsih C, Kurniawan A, Lugito NPH. Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. Int J Med Rev Case Rep. (2021), [cited April 02, 2025]; 5(2): 25-30. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Harvard Style

Cucunawangsih, C., Kurniawan, . A. & Lugito, . N. P. H. (2021) Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. Int J Med Rev Case Rep, 5 (2), 25-30. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Turabian Style

Cucunawangsih, Cucunawangsih, Andree Kurniawan, and Nata Pratama Hardjo Lugito. 2021. Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. International Journal of Medical Reviews and Case Reports, 5 (2), 25-30. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Chicago Style

Cucunawangsih, Cucunawangsih, Andree Kurniawan, and Nata Pratama Hardjo Lugito. "Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report." International Journal of Medical Reviews and Case Reports 5 (2021), 25-30. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


MLA (The Modern Language Association) Style

Cucunawangsih, Cucunawangsih, Andree Kurniawan, and Nata Pratama Hardjo Lugito. "Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report." International Journal of Medical Reviews and Case Reports 5.2 (2021), 25-30. Print. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


APA (American Psychological Association) Style

Cucunawangsih, C., Kurniawan, . A. & Lugito, . N. P. H. (2021) Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. International Journal of Medical Reviews and Case Reports, 5 (2), 25-30. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


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