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2021, Vol: 5, Issue: 1
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Case Report 


Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report

Cucunawangsih Cucunawangsih , Andree Kurniawan , Nata Pratama Hardjo Lugito .

Abstract
Micafungin is an echinocandin-class antifungal agent that is extremely used in the recent era due to minimal toxicity and broad-spectrum activity, unfortunately has limited ability against Cryptococcus neoformans. Since it’s inherently resistant, indeed disseminated invasive cryptococcosis is becoming an important issue in echinocandin recipient with impaired immunity. We present a patient with systemic lupus erythematosus and miliary tuberculosis, who developed a fungal infection with invasive cryptococcal fungemia during empirical micafungin therapy. To the best our knowledge, breakthrough disseminated cryptococcosis has not been reported, as seen in our patient. This case highlighted that Cryptococcus neoformans infection should be keep in mind as a possible breakthrough infection while receiving echinocandin, especially in patients with cellular immunodeficiency.

Key words: invasive fungal infection, micafungin, Cryptococcus neoformans


 
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How to Cite this Article
Pubmed Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia

Web Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. http://www.mdpub.net/?mno=13481 [Access: March 12, 2021]. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia

AMA (American Medical Association) Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Vancouver/ICMJE Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Harvard Style

, C. C., , A. K., , N. P. H. L. & (2021) Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Turabian Style

, Cucunawangsih Cucunawangsih, Andree Kurniawan, Nata Pratama Hardjo Lugito, and . 2021. Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Chicago Style

, Cucunawangsih Cucunawangsih, Andree Kurniawan, Nata Pratama Hardjo Lugito, and . "Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report." doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


MLA (The Modern Language Association) Style

, Cucunawangsih Cucunawangsih, Andree Kurniawan, Nata Pratama Hardjo Lugito, and . "Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report." doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


APA (American Psychological Association) Style

, C. C., , A. K., , N. P. H. L. & (2021) Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


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