E-ISSN 2534-9821
 

Case Report 


Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report

Cucunawangsih Cucunawangsih , Andree Kurniawan , Nata Pratama Hardjo Lugito .

Abstract
Micafungin is an echinocandin-class antifungal agent that is extremely used in the recent era due to minimal toxicity and broad-spectrum activity, unfortunately has limited ability against Cryptococcus neoformans. Since itís inherently resistant, indeed disseminated invasive cryptococcosis is becoming an important issue in echinocandin recipient with impaired immunity. We present a patient with systemic lupus erythematosus and miliary tuberculosis, who developed a fungal infection with invasive cryptococcal fungemia during empirical micafungin therapy. To the best our knowledge, breakthrough disseminated cryptococcosis has not been reported, as seen in our patient. This case highlighted that Cryptococcus neoformans infection should be keep in mind as a possible breakthrough infection while receiving echinocandin, especially in patients with cellular immunodeficiency.

Key words: invasive fungal infection, micafungin, Cryptococcus neoformans


 
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How to Cite this Article
Pubmed Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


Web Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. http://www.mdpub.net/?mno=13481 [Access: March 12, 2021]. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia


AMA (American Medical Association) Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia



Vancouver/ICMJE Style

CC, AK, NPHL, . Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia



Harvard Style

, C. C., , A. K., , N. P. H. L. & (2021) Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia



Turabian Style

, Cucunawangsih Cucunawangsih, Andree Kurniawan, Nata Pratama Hardjo Lugito, and . 2021. Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia



Chicago Style

, Cucunawangsih Cucunawangsih, Andree Kurniawan, Nata Pratama Hardjo Lugito, and . "Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report." doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia



MLA (The Modern Language Association) Style

, Cucunawangsih Cucunawangsih, Andree Kurniawan, Nata Pratama Hardjo Lugito, and . "Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report." doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia



APA (American Psychological Association) Style

, C. C., , A. K., , N. P. H. L. & (2021) Breakthrough Invasive Disseminated Cryptococcal Fungemia in a Patient Receiving Micafungin Therapy: A Case Report. doi:10.5455/IJMRCR.Disseminated-Cryptococcal-Fungemia