E-ISSN 2534-9821
 

Case Report 


Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis

Gusti Ngurah Arika, Gede Kambayana, Pande Ketut Kurniari.

Abstract
Sistemic Lupus Erythematosus (SLE) is a chronic multisystem inflammatory autoimmune disease with unknown etiology and broad clinical spectrum presentation. In several case, there is cross-reaction between anti-DNA antibody and-N-methyl-D-Aspartate Receptor (NMDAR) subunit 2 (NR2) that can implicated to multiple brain disorders including stroke, chronic neurodegeneration, epilepsy, and schizophrenia. SLE with anti-NMDAR encepalitis are rare cases and there was difficulty in establishing the diagnosis and providing therapy because of symptoms and signs in patients who are not specific and there is no established therapeutic protocol for this disease. A 15-year-old female with encephalitis cause by neuropsichyatric SLE and anti-NMDAR which was successfully treated with highdose steroid followed by administration of cyclophosphamide and rituximab.

Key words: SLE, Encephalitis, Anti-NMDAR


 
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How to Cite this Article
Pubmed Style

Arika GN, Kambayana G, Kurniari PK. Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis. Int J Med Rev Case Rep. 2020; 4(12): 43-45. doi:10.5455/IJMRCR.lupus-enchepalitis


Web Style

Arika GN, Kambayana G, Kurniari PK. Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis. http://www.mdpub.net/?mno=113328 [Access: January 31, 2021]. doi:10.5455/IJMRCR.lupus-enchepalitis


AMA (American Medical Association) Style

Arika GN, Kambayana G, Kurniari PK. Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis. Int J Med Rev Case Rep. 2020; 4(12): 43-45. doi:10.5455/IJMRCR.lupus-enchepalitis



Vancouver/ICMJE Style

Arika GN, Kambayana G, Kurniari PK. Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis. Int J Med Rev Case Rep. (2020), [cited January 31, 2021]; 4(12): 43-45. doi:10.5455/IJMRCR.lupus-enchepalitis



Harvard Style

Arika, G. N., Kambayana, . G. & Kurniari, . P. K. (2020) Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis. Int J Med Rev Case Rep, 4 (12), 43-45. doi:10.5455/IJMRCR.lupus-enchepalitis



Turabian Style

Arika, Gusti Ngurah, Gede Kambayana, and Pande Ketut Kurniari. 2020. Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis. International Journal of Medical Reviews and Case Reports, 4 (12), 43-45. doi:10.5455/IJMRCR.lupus-enchepalitis



Chicago Style

Arika, Gusti Ngurah, Gede Kambayana, and Pande Ketut Kurniari. "Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis." International Journal of Medical Reviews and Case Reports 4 (2020), 43-45. doi:10.5455/IJMRCR.lupus-enchepalitis



MLA (The Modern Language Association) Style

Arika, Gusti Ngurah, Gede Kambayana, and Pande Ketut Kurniari. "Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis." International Journal of Medical Reviews and Case Reports 4.12 (2020), 43-45. Print. doi:10.5455/IJMRCR.lupus-enchepalitis



APA (American Psychological Association) Style

Arika, G. N., Kambayana, . G. & Kurniari, . P. K. (2020) Diagnostic and management problems in patient with systemic lupus erythematosus (SLE) and anti N-methyl-D-Aspartate receptor (NMDAR) encephalitis. International Journal of Medical Reviews and Case Reports, 4 (12), 43-45. doi:10.5455/IJMRCR.lupus-enchepalitis