Abstract
Introduction: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Brain metastases originating from PTC is extremely rare, presents only in 0.4-1.2% of all PTC cases. PTC presenting with distant metastasis has less favourable outcome.

Case Presentation: A 67-years-old female patient presented with a painless and progressively enlarging lump on the forehead since 2 years before admitted. Patient also claimed to have a slow-growing neck swelling over 5 years. Physical examination revealed mass on forehead, and multiple nodules on thyroid. Fine Needle Aspiration Biopsy (FNAB) of neck mass was performed and PTC was confirmed. Head Multi Sliced Computed Tomography (MSCT) examination was performed to evaluate forehead mass and revealed heterogeneous extra axial mass (8.5 x 6.4 x 7.3 cm) in the left frontal lobe. Patient underwent tumor resection and the postoperative histopathologic examination confirmed metastases of PTC. Thyroidectomy was recommended but patient refused to undergo further intervention.

Conclusions: Early detection and treatment of PTC is crucial as distant metastases may develop and reduce the survival rate.

Key words: thyroid carcinoma, papillary thyroid carcinoma, brain metastases