E-ISSN 2534-9821
 

Original Research 


Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy

Fathul Yazid Izza, Endang Kustiowati, Widiastuti M.I, Dodik Tugasworo, Dani Rahmawati, Trianggoro Budisulistyo.

Abstract
Introduction: Pain is one of the complaints from breast cancer patients who received chemotherapy. One of the side effects of chemotherapy to breast cancer patients is neuronal damage resulting in neuropathic pain. The increased incidence of neuropathic pain in chemotherapy patients often results in impaired activity. This study was conducted to determine the correlation between neuropathic pain and impaired daily activity before the first injection and after the third injection in breast cancer patients receiving chemotherapy.

Methods: This was an observational analytic study with a prospective cohort design. The subjects were postoperative breast cancer patients who received chemotherapy at the Kasuari Ward, Dr Kariadi Hospital, Semarang, who fulfilled the inclusion and exclusion criteria. It was conducted from September 2019 to February 2020. Examination of neuropathic pain and pain scoring was assessed using the LANSS questionnaire and Brief Pain Inventory (BPI). Data were analyzed using Spearman's bivariate correlation test. The results were significant if the p-value <0.05.

Results: 23 breast cancer patients who received chemotherapy at the Kasuari Ward, Dr Kariadi Hospital, Semarang participated in this study. The incidence of neuropathic pain increased after the third injection of chemotherapy. The correlation between pain score and activity disorder score before the first chemotherapy was significant (p = 0,000; rho = 0.697) and after the third chemotherapy was also significant (p = 0.045; rho = 0.421). In addition, there was a strong correlation between pain score and activity disorder score after third chemotherapy being controlled with age (p = 0.003; rho = 0.589).

Conclusions: There was an increased of neuropathic pain and activity disorder after the third injection of chemotherapy. There was a correlation between pain scores and activity disorder in breast cancer patients receiving chemotherapy.

Key words: Breast cancer, neuropathic pain, chemotherapy, activity disorders


 
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How to Cite this Article
Pubmed Style

Izza FY, Kustiowati E, M.I W, Tugasworo D, Rahmawati D, Budisulistyo T. Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy. doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER


Web Style

Izza FY, Kustiowati E, M.I W, Tugasworo D, Rahmawati D, Budisulistyo T. Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy. http://www.mdpub.net/?mno=6874 [Access: March 12, 2021]. doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER


AMA (American Medical Association) Style

Izza FY, Kustiowati E, M.I W, Tugasworo D, Rahmawati D, Budisulistyo T. Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy. doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER



Vancouver/ICMJE Style

Izza FY, Kustiowati E, M.I W, Tugasworo D, Rahmawati D, Budisulistyo T. Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy. doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER



Harvard Style

Izza, F. Y., Kustiowati, . E., M.I, . W., Tugasworo, . D., Rahmawati, . D. & Budisulistyo, . T. (2021) Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy. doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER



Turabian Style

Izza, Fathul Yazid, Endang Kustiowati, Widiastuti M.I, Dodik Tugasworo, Dani Rahmawati, and Trianggoro Budisulistyo. 2021. Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy. doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER



Chicago Style

Izza, Fathul Yazid, Endang Kustiowati, Widiastuti M.I, Dodik Tugasworo, Dani Rahmawati, and Trianggoro Budisulistyo. "Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy." doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER



MLA (The Modern Language Association) Style

Izza, Fathul Yazid, Endang Kustiowati, Widiastuti M.I, Dodik Tugasworo, Dani Rahmawati, and Trianggoro Budisulistyo. "Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy." doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER



APA (American Psychological Association) Style

Izza, F. Y., Kustiowati, . E., M.I, . W., Tugasworo, . D., Rahmawati, . D. & Budisulistyo, . T. (2021) Neuropathic pain and activity disorders in breast cancer patients receiving chemotherapy. doi:10.5455/IJMRCR.NEUROPATHIC-PAIN-ACTIVITY-DISORDERS-IN-BREAST-CANCER