E-ISSN 2534-9821
 

Case Report 


Cholestatic hepatitis as a presentation of Epstein-Barr virus infection

Mayara Nogueira, Joana Gaspar, Susana Gomes.

Abstract
Epstein-Barr virus (EBV) infection in children and adolescents clinically presents as infectious mononucleosis and usually leads to self limited elevation of liver enzymes but cholestatic hepatitis with jaundice is rare. We present a 16-year-old female with fever, fatigue, vomitting, choluria and jaundice. Physical examination showed a painful abdomen and the remaining examination was unremarkable. Laboratory tests results revealed leucocytosis and activated lymphocytes, normal haemoglobin level, elevation of transaminases more than 7 times the upper limit, cholestasis and hypoabuminemia. The abdominal ultrasound showed mild hepatosplenomegaly. Viral serologies revealed positive EBV viral capsid antibody IgM and negative IgG and were negative for other viral agents. Later she developed haemolytic anaemia. She received support treatment and fully recovered. We emphasize that EBV infection should be considered in patients with cholestatic hepatitis with jaundice.

Key words: Epstein-Barr virus, cholestasis, hepatitis, hyperbilirubinemia, jaundice.


 
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How to Cite this Article
Pubmed Style

Nogueira M, Gaspar J, Gomes S, . Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


Web Style

Nogueira M, Gaspar J, Gomes S, . Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. http://www.mdpub.net/?mno=53293 [Access: March 17, 2021]. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


AMA (American Medical Association) Style

Nogueira M, Gaspar J, Gomes S, . Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Vancouver/ICMJE Style

Nogueira M, Gaspar J, Gomes S, . Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Harvard Style

Nogueira, M., Gaspar, J., Gomes, S. & (2021) Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Turabian Style

Nogueira, Mayara, Joana Gaspar, Susana Gomes, and . 2021. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Chicago Style

Nogueira, Mayara, Joana Gaspar, Susana Gomes, and . "Cholestatic hepatitis as a presentation of Epstein-Barr virus infection." doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



MLA (The Modern Language Association) Style

Nogueira, Mayara, Joana Gaspar, Susana Gomes, and . "Cholestatic hepatitis as a presentation of Epstein-Barr virus infection." doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



APA (American Psychological Association) Style

Nogueira, M., Gaspar, J., Gomes, S. & (2021) Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058