E-ISSN 2534-9821
 

Original Research 


Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate

Ram Bahadur Rai, Th. Dinesh Singh, P. Nishikanta Singh, Bhawana Rai, Aradhna Nazareth.

Abstract
Background:
Both inductions of anaesthesia and airway management are the critical part of conducting general anaesthesia. The common complications following injection of induction agent especially in hemodynamically unstable patients range from hypotension to arrhythmias subsequently leading to cardiovascular collapse. Conversely, airway manipulation during laryngoscopy and tracheal Intubation may cause arrhythmias, hypertension, myocardial injury, airway spasm, hypoxia, hypercarbia, and raised intracranial and intraocular pressure.
Aims and Objective:
To compare the hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. It is also to compare the incidence of myoclonus, oxygen saturation and postoperative nausea and vomiting.
Materials and methods:
One hundred thirty American Society of Anaesthesiology grade I and II patients of age group 18-50 years scheduled for the planned surgical procedure under general anaesthesia were randomly divided into two groups of 65 each receiving Propofol 2 mg/kg and Etomidate 0.3 mg/kg as an induction agent. Vital parameters were measured at induction and after intubation for comparison. Myoclonus and oxygenation saturation was noted after induction.
Results:
Both groups are comparable in terms of demographic variables. The statistical evaluation showed that the decrease in blood pressure was statistically significant (p<0.05) in group P on induction whereas there is a significant (p<0.05) increase in blood pressure and heart rate in group E after intubation. There was no difference with regard to oxygen saturation and postoperative nausea and vomiting.
Conclusion:
Etomidate is a more hemodynamically stable induction agent compared to Propofol but is less effective in preventing stress response to laryngoscopy and tracheal intubation with a higher incidence of myoclonus on induction if proper premedication is not used.

Key words: Hemodynamic Response, Induction Agent, Laryngoscopy, Myoclonus, Tracheal Intubation


 
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How to Cite this Article
Pubmed Style

Rai RB, Singh TD, Singh PN, Rai B, Nazareth A. Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. Int J Med Rev Case Rep. 2022; 6(4): 86-91. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy


Web Style

Rai RB, Singh TD, Singh PN, Rai B, Nazareth A. Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. https://www.mdpub.net/?mno=125938 [Access: June 12, 2022]. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy


AMA (American Medical Association) Style

Rai RB, Singh TD, Singh PN, Rai B, Nazareth A. Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. Int J Med Rev Case Rep. 2022; 6(4): 86-91. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy



Vancouver/ICMJE Style

Rai RB, Singh TD, Singh PN, Rai B, Nazareth A. Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. Int J Med Rev Case Rep. (2022), [cited June 12, 2022]; 6(4): 86-91. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy



Harvard Style

Rai, R. B., Singh, . T. D., Singh, . P. N., Rai, . B. & Nazareth, . A. (2022) Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. Int J Med Rev Case Rep, 6 (4), 86-91. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy



Turabian Style

Rai, Ram Bahadur, Th. Dinesh Singh, P. Nishikanta Singh, Bhawana Rai, and Aradhna Nazareth. 2022. Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. International Journal of Medical Reviews and Case Reports, 6 (4), 86-91. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy



Chicago Style

Rai, Ram Bahadur, Th. Dinesh Singh, P. Nishikanta Singh, Bhawana Rai, and Aradhna Nazareth. "Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate." International Journal of Medical Reviews and Case Reports 6 (2022), 86-91. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy



MLA (The Modern Language Association) Style

Rai, Ram Bahadur, Th. Dinesh Singh, P. Nishikanta Singh, Bhawana Rai, and Aradhna Nazareth. "Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate." International Journal of Medical Reviews and Case Reports 6.4 (2022), 86-91. Print. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy



APA (American Psychological Association) Style

Rai, R. B., Singh, . T. D., Singh, . P. N., Rai, . B. & Nazareth, . A. (2022) Comparison of hemodynamic response to laryngoscopy and tracheal Intubation after induction of anaesthesia by Propofol and Etomidate. International Journal of Medical Reviews and Case Reports, 6 (4), 86-91. doi:10.5455/IJMRCR.hemodynamicresponsetolaryngoscopy