Abstract
Objectives: Colonic mucosal pseudolipomatosis is an uncommonly seen condition and knowledge on its pathogenesis is still not enough. It is a benign entity and usually remains asymptomatic.
Patients; During a 4 month period, we found pseudolipomatosis coli in 11 of 528 colonoscopy cases(2.08%).
Results; The pseudolipomatosis lesions presented as slightly elevated whitish-yellowish plaques measuring from a few milimeters to 2 cm for the longest dimension. The plaques extended over 5-6 cm segment. The lesions were localizated in proximal colon. Biopsy specimen was taken from all these lesions and all biopsies were diagnosed as colonic mucosal pseudolipomatosis by pathologist. No related microorganisms or parasites were seen.
We could not find any relation between the type of material used during bowel preparing and colonic mucosal pseudolipomatosis. We found that automated endoscope disinfectant machine was broken for almost 2 years and during this period the scopes disinfection was done manually by using anioxide 1000 solution (peracetic acid, 3% hydrogen peroxide). After repair of the machine and changing the solution, we haven’t observed any case.
Conclusion ; Stemming from manual colonoscope disinfection, residual hydrogen peroxide may ease the formation of colonic mucosal pseudolipomatosis. After changing the solution and starting to use the machine, no patient with colonic mucosal pseudolipomatosis was diagnosed. Therefore using automated endoscope disinfectant machine is required.

Key words: Colonic mucosal pseudolipomatosis, Peracetic acid, Automated endoscope disinfectant machine