Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs

Jainal Arifin; Karya Triko Biakto; Andry Usman; Muh Nasrum Massi; Nur Rahmansyah; Mirza Ariandi; Padlan Pasallo; Ery Wildan

doi:10.5455/IJMRCR.spine-tuberculosis

2023, Vol: 7, Issue: 6

7 / 6Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

Copyright Transfer Form

« Previous Article

Original Research

Online Publishing Date:
16 / 10 / 2019

Int J Med Rev Case Rep. 2019; 3(12): 819-822

doi: 10.5455/IJMRCR.spine-tuberculosis

Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs

Jainal Arifin, Karya Triko Biakto, Andry Usman, Muh Nasrum Massi, Nur Rahmansyah, Mirza Ariandi, Padlan Pasallo, Ery Wildan.

Abstract
Spinal Tuberculosis is an infection of the spine caused by Mycobacterium Tuberculosis. It is an extrapulmonary complication of Mycobacterium Tuberculosis infection. The purpose of this study was to determine whether there is a NOS 2A gene polymorphism so that patients are susceptible to tuberculosis spondylitis. This study is an analytical cross-sectional study on 36 Spinal tuberculosis patients at the Wahidin Sudirohusodo Hospital in Makassar who had tested positive TB geneXpert and took 5 ml of blood samples in EDTA tubes. Then DNA extraction and genotyping examination with PCR techniques were carried out.
There were 39 subjects in this study 39 TB spondylitis patients (84.8%) and 7 controls (15.2%). Most of them were women (58.7%), aged between 20-29 years (41.3%). Based on PCR results, only 2 subjects experienced a gene mutation (4.3%) in the A-277G single nucleotide. The NOS2A gene polymorphism is a cause of susceptibility to spinal tuberculosis.

Key words: Spinal Tuberculosis, Polymorphism, Inducible Nitric Oxide Synthase, NOS 2A

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Jainal Arifin Articles by Karya Triko Biakto Articles by Andry Usman Articles by Muh Nasrum Massi Articles by Nur Rahmansyah Articles by Mirza Ariandi Articles by Padlan Pasallo Articles by Ery Wildan
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Arifin J, Biakto KT, Usman A, Massi MN, Rahmansyah N, Ariandi M, Pasallo P, Wildan E. Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs. Int J Med Rev Case Rep. 2019; 3(12): 819-822. doi:10.5455/IJMRCR.spine-tuberculosis

Web Style

Arifin J, Biakto KT, Usman A, Massi MN, Rahmansyah N, Ariandi M, Pasallo P, Wildan E. Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs. https://www.mdpub.net/?mno=48607 [Access: April 04, 2024]. doi:10.5455/IJMRCR.spine-tuberculosis

AMA (American Medical Association) Style

Arifin J, Biakto KT, Usman A, Massi MN, Rahmansyah N, Ariandi M, Pasallo P, Wildan E. Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs. Int J Med Rev Case Rep. 2019; 3(12): 819-822. doi:10.5455/IJMRCR.spine-tuberculosis

Vancouver/ICMJE Style

Arifin J, Biakto KT, Usman A, Massi MN, Rahmansyah N, Ariandi M, Pasallo P, Wildan E. Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs. Int J Med Rev Case Rep. (2019), [cited April 04, 2024]; 3(12): 819-822. doi:10.5455/IJMRCR.spine-tuberculosis

Harvard Style

Arifin, J., Biakto, . K. T., Usman, . A., Massi, . M. N., Rahmansyah, . N., Ariandi, . M., Pasallo, . P. & Wildan, . E. (2019) Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs. Int J Med Rev Case Rep, 3 (12), 819-822. doi:10.5455/IJMRCR.spine-tuberculosis

Turabian Style

Arifin, Jainal, Karya Triko Biakto, Andry Usman, Muh Nasrum Massi, Nur Rahmansyah, Mirza Ariandi, Padlan Pasallo, and Ery Wildan. 2019. Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs. International Journal of Medical Reviews and Case Reports, 3 (12), 819-822. doi:10.5455/IJMRCR.spine-tuberculosis

Chicago Style

Arifin, Jainal, Karya Triko Biakto, Andry Usman, Muh Nasrum Massi, Nur Rahmansyah, Mirza Ariandi, Padlan Pasallo, and Ery Wildan. "Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs." International Journal of Medical Reviews and Case Reports 3 (2019), 819-822. doi:10.5455/IJMRCR.spine-tuberculosis

MLA (The Modern Language Association) Style

Arifin, Jainal, Karya Triko Biakto, Andry Usman, Muh Nasrum Massi, Nur Rahmansyah, Mirza Ariandi, Padlan Pasallo, and Ery Wildan. "Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs." International Journal of Medical Reviews and Case Reports 3.12 (2019), 819-822. Print. doi:10.5455/IJMRCR.spine-tuberculosis

APA (American Psychological Association) Style

Arifin, J., Biakto, . K. T., Usman, . A., Massi, . M. N., Rahmansyah, . N., Ariandi, . M., Pasallo, . P. & Wildan, . E. (2019) Polymorphısm ın the inducıble nıtrıc oxıde synthase gene ınpatıent susceptıbılıty spınal tuberculosıs. International Journal of Medical Reviews and Case Reports, 3 (12), 819-822. doi:10.5455/IJMRCR.spine-tuberculosis

About International Journal of Medical Reviews and Case Reports

International Journal of Medical Reviews and Case Reports (Int J Med Rev Case Rep)ISSN: 2534-9821The International Journal of Medical Reviews and Ca ... Read more.

For best results, please use Internet Explorer or Google Chrome.

Contact Information

Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the International Journal of Medical Reviews and Case Reports editorial office as follows:

Bulgarian Association of Young Surgeons (BAYS);

National Center of Public Health and Analyses (NCPHA), floor 2, office № 31, Sofia 1431, Bulgaria.

inkov@journalmedica.com

Financial department is managed by International Sci Ink Press.

It is a company registered in Bulgaria with registered no. 205414288 and registered address at 57 Antim I str., Vazrazhdane, Sofia, 1303, Bulgaria.

Tel: +359883427500

About International Journal of Medical Reviews and Case Reports

Contact Information

How to cite this article