E-ISSN 2534-9821
 

Case Report

Online Publishing Date:
27 / 12 / 2021

 


Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin

Kevin Verhoeff, Curtis Budden, Leah Remington, Shelley Duggan, Rajive Jassal.


Abstract
Introduction:
Botulism is a rare neuroparalytic disease requiring rapid identification and treatment. Foodborne toxaemia is well described but intestinal toxaemia is rare. Gastrointestinal (GI) abnormalities allow Clostridium botulinum to colonize the GI tract and release toxin systemically. Intestinal toxaemia has a unique protracted presentation with increased morbidity and mortality. Diagnosis is complicated by limited experience and conditions with similar symmetric descending paralysis.

Case Report:
We discuss intestinal toxaemia in a 48-year-old male with inflammatory bowel disease, who required a 140-day hospital stay including extensive intensive care management. We review the literature and outline the acute presentation, diagnosis, and empiric treatment with botulism antitoxin.

Conclusion:
Intestinal toxaemia is a unique clinical entity with a protracted course and increased morbidity and mortality. Patients with GI abnormalities are at risk and early identification with empiric antitoxin treatment is crucial.

Key words: Botulism, Paralysis, Clostridium, Toxemia, Intestinal, Electromyography


 
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How to Cite this Article
Pubmed Style

Verhoeff K, Budden C, Remington L, Duggan S, Jassal R. Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin. Int J Med Rev Case Rep. 2021; 5(10): 61-64. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU


Web Style

Verhoeff K, Budden C, Remington L, Duggan S, Jassal R. Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin. https://www.mdpub.net/?mno=86199 [Access: April 04, 2024]. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU


AMA (American Medical Association) Style

Verhoeff K, Budden C, Remington L, Duggan S, Jassal R. Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin. Int J Med Rev Case Rep. 2021; 5(10): 61-64. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU



Vancouver/ICMJE Style

Verhoeff K, Budden C, Remington L, Duggan S, Jassal R. Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin. Int J Med Rev Case Rep. (2021), [cited April 04, 2024]; 5(10): 61-64. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU



Harvard Style

Verhoeff, K., Budden, . C., Remington, . L., Duggan, . S. & Jassal, . R. (2021) Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin. Int J Med Rev Case Rep, 5 (10), 61-64. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU



Turabian Style

Verhoeff, Kevin, Curtis Budden, Leah Remington, Shelley Duggan, and Rajive Jassal. 2021. Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin. International Journal of Medical Reviews and Case Reports, 5 (10), 61-64. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU



Chicago Style

Verhoeff, Kevin, Curtis Budden, Leah Remington, Shelley Duggan, and Rajive Jassal. "Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin." International Journal of Medical Reviews and Case Reports 5 (2021), 61-64. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU



MLA (The Modern Language Association) Style

Verhoeff, Kevin, Curtis Budden, Leah Remington, Shelley Duggan, and Rajive Jassal. "Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin." International Journal of Medical Reviews and Case Reports 5.10 (2021), 61-64. Print. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU



APA (American Psychological Association) Style

Verhoeff, K., Budden, . C., Remington, . L., Duggan, . S. & Jassal, . R. (2021) Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin. International Journal of Medical Reviews and Case Reports, 5 (10), 61-64. doi:10.5455/IJMRCR.IntestinalSelfInoculationofBotulismintheICU