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Online Publishing Date:
25 / 12 / 2020

 


Immediate postpartum depression and the NT-3 gene

Valeria Velazquez Jaramillo, Arturo Gonzalez Santana, Araceli Consuelo Hinojosa Juarez, Joel Alberto Vargas Hernandez, Hugo Mendieta Zeron.


Abstract
Introduction: Postpartum depression has a prevalence range from 6.5% to 12.9%. The NT-3 gene is involved in alterations in patients with mood disorders. Purpose: The aim was to describe a possible correlation between the NT-3 expression and the Edinburgh Postnatal Depression Scale (EPDS). Material and Methods: It was a clinical, comparative, prospective and cross-sectional study. Puerperal women were asked to answer the EPDS while mRNA was extracted from peripheral blood and through the qPCR the relative expression of NT-3 was determined using the delta-delta- (CT) method (2-ΔΔCT). Results and Discussion: The NT-3 expression was quantified in 5 patients with depression and 6 healthy women. A fold change of 1.7 was obtained when the NT-3 is present in the group with depression in relation to the control group. Also, a positive significant correlation was found between the gene relative expression and the EPDS score (r2 = 0.60516, p = 0.04853). The fold change when the NT-3 is expressed means a risk to develop puerperal depression in our population, which is visualized as an inevitable disease for a wide range of patients. Conclusion: It was concluded that the NT-3 gene is effectively correlated with the EPDS score and explains, in part, a subgroup of patients that will develop this health complication.

Key words: Edinburgh Postnatal Depression Scale, NT-3, postpartum depression


 
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How to Cite this Article
Pubmed Style

Jaramillo VV, Santana AG, Juarez ACH, Hernandez JAV, Zeron HM. Immediate postpartum depression and the NT-3 gene. Int J Med Rev Case Rep. 2020; 4(10): 135-138. doi:10.5455/IJMRCR.Immediate-postpartum-depression

Web Style

Jaramillo VV, Santana AG, Juarez ACH, Hernandez JAV, Zeron HM. Immediate postpartum depression and the NT-3 gene. https://www.mdpub.net/?mno=2082 [Access: April 04, 2024]. doi:10.5455/IJMRCR.Immediate-postpartum-depression

AMA (American Medical Association) Style

Jaramillo VV, Santana AG, Juarez ACH, Hernandez JAV, Zeron HM. Immediate postpartum depression and the NT-3 gene. Int J Med Rev Case Rep. 2020; 4(10): 135-138. doi:10.5455/IJMRCR.Immediate-postpartum-depression


Vancouver/ICMJE Style

Jaramillo VV, Santana AG, Juarez ACH, Hernandez JAV, Zeron HM. Immediate postpartum depression and the NT-3 gene. Int J Med Rev Case Rep. (2020), [cited April 04, 2024]; 4(10): 135-138. doi:10.5455/IJMRCR.Immediate-postpartum-depression


Harvard Style

Jaramillo, V. V., Santana, . A. G., Juarez, . A. C. H., Hernandez, . J. A. V. & Zeron, . H. M. (2020) Immediate postpartum depression and the NT-3 gene. Int J Med Rev Case Rep, 4 (10), 135-138. doi:10.5455/IJMRCR.Immediate-postpartum-depression


Turabian Style

Jaramillo, Valeria Velazquez, Arturo Gonzalez Santana, Araceli Consuelo Hinojosa Juarez, Joel Alberto Vargas Hernandez, and Hugo Mendieta Zeron. 2020. Immediate postpartum depression and the NT-3 gene. International Journal of Medical Reviews and Case Reports, 4 (10), 135-138. doi:10.5455/IJMRCR.Immediate-postpartum-depression


Chicago Style

Jaramillo, Valeria Velazquez, Arturo Gonzalez Santana, Araceli Consuelo Hinojosa Juarez, Joel Alberto Vargas Hernandez, and Hugo Mendieta Zeron. "Immediate postpartum depression and the NT-3 gene." International Journal of Medical Reviews and Case Reports 4 (2020), 135-138. doi:10.5455/IJMRCR.Immediate-postpartum-depression


MLA (The Modern Language Association) Style

Jaramillo, Valeria Velazquez, Arturo Gonzalez Santana, Araceli Consuelo Hinojosa Juarez, Joel Alberto Vargas Hernandez, and Hugo Mendieta Zeron. "Immediate postpartum depression and the NT-3 gene." International Journal of Medical Reviews and Case Reports 4.10 (2020), 135-138. Print. doi:10.5455/IJMRCR.Immediate-postpartum-depression


APA (American Psychological Association) Style

Jaramillo, V. V., Santana, . A. G., Juarez, . A. C. H., Hernandez, . J. A. V. & Zeron, . H. M. (2020) Immediate postpartum depression and the NT-3 gene. International Journal of Medical Reviews and Case Reports, 4 (10), 135-138. doi:10.5455/IJMRCR.Immediate-postpartum-depression


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